Cargando…
Specific SKN-1/Nrf Stress Responses to Perturbations in Translation Elongation and Proteasome Activity
SKN-1, the Caenorhabditis elegans Nrf1/2/3 ortholog, promotes both oxidative stress resistance and longevity. SKN-1 responds to oxidative stress by upregulating genes that detoxify and defend against free radicals and other reactive molecules, a SKN-1/Nrf function that is both well-known and conserv...
Autores principales: | Li, Xuan, Matilainen, Olli, Jin, Congyu, Glover-Cutter, Kira M., Holmberg, Carina I., Blackwell, T. Keith |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111486/ https://www.ncbi.nlm.nih.gov/pubmed/21695230 http://dx.doi.org/10.1371/journal.pgen.1002119 |
Ejemplares similares
-
Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf
por: Glover-Cutter, Kira M., et al.
Publicado: (2013) -
Tissue-specific effects of temperature on proteasome function
por: Pispa, Johanna, et al.
Publicado: (2020) -
Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence
por: Steinbaugh, Michael J, et al.
Publicado: (2015) -
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
por: Lehrbach, Nicolas J, et al.
Publicado: (2016) -
Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf
por: Ogawa, Takahiro, et al.
Publicado: (2016)