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Mutual Inactivation of Notch Receptors and Ligands Facilitates Developmental Patterning

Developmental patterning requires juxtacrine signaling in order to tightly coordinate the fates of neighboring cells. Recent work has shown that Notch and Delta, the canonical metazoan juxtacrine signaling receptor and ligand, mutually inactivate each other in the same cell. This cis-interaction gen...

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Detalles Bibliográficos
Autores principales:	Sprinzak, David, Lakhanpal, Amit, LeBon, Lauren, Garcia-Ojalvo, Jordi, Elowitz, Michael B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111533/ https://www.ncbi.nlm.nih.gov/pubmed/21695234 http://dx.doi.org/10.1371/journal.pcbi.1002069

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