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Coronavirus Gene 7 Counteracts Host Defenses and Modulates Virus Virulence

Transmissible gastroenteritis virus (TGEV) genome contains three accessory genes: 3a, 3b and 7. Gene 7 is only present in members of coronavirus genus a1, and encodes a hydrophobic protein of 78 aa. To study gene 7 function, a recombinant TGEV virus lacking gene 7 was engineered (rTGEV-Δ7). Both the...

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Detalles Bibliográficos
Autores principales:	Cruz, Jazmina L. G., Sola, Isabel, Becares, Martina, Alberca, Berta, Plana, Joan, Enjuanes, Luis, Zuñiga, Sonia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111541/ https://www.ncbi.nlm.nih.gov/pubmed/21695242 http://dx.doi.org/10.1371/journal.ppat.1002090

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