The IGS Standard Operating Procedure for Automated Prokaryotic Annotation

The Institute for Genome Sciences (IGS) has developed a prokaryotic annotation pipeline that is used for coding gene/RNA prediction and functional annotation of Bacteria and Archaea. The fully automated pipeline accepts one or many genomic sequences as input and produces output in a variety of stand...

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Detalles Bibliográficos
Autores principales: Galens, Kevin, Orvis, Joshua, Daugherty, Sean, Creasy, Heather H., Angiuoli, Sam, White, Owen, Wortman, Jennifer, Mahurkar, Anup, Giglio, Michelle Gwinn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Michigan State University 2011
Materias:
Short Genome Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111993/
https://www.ncbi.nlm.nih.gov/pubmed/21677861
http://dx.doi.org/10.4056/sigs.1223234
Descripción
Sumario:The Institute for Genome Sciences (IGS) has developed a prokaryotic annotation pipeline that is used for coding gene/RNA prediction and functional annotation of Bacteria and Archaea. The fully automated pipeline accepts one or many genomic sequences as input and produces output in a variety of standard formats. Functional annotation is primarily based on similarity searches and motif finding combined with a hierarchical rule based annotation system. The output annotations can also be loaded into a relational database and accessed through visualization tools.

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