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Protein coalitions in a core mammalian biochemical network linked by rapidly evolving proteins
BACKGROUND: Cellular ATP levels are generated by glucose-stimulated mitochondrial metabolism and determine metabolic responses, such as glucose-stimulated insulin secretion (GSIS) from the β-cells of pancreatic islets. We describe an analysis of the evolutionary processes affecting the core enzymes...
Autores principales: | Ainali, Chrysanthi, Simon, Michelle, Freilich, Shiri, Espinosa, Octavio, Hazelwood, Lee, Tsoka, Sophia, Ouzounis, Christos A, Hancock, John M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112093/ https://www.ncbi.nlm.nih.gov/pubmed/21612628 http://dx.doi.org/10.1186/1471-2148-11-142 |
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