Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness

BACKGROUND: One of the hallmarks of Alzheimer's disease, and several other degenerative disorders such as Inclusion Body Myositis, is the abnormal accumulation of amyloid precursor protein (APP) and its proteolytic amyloid peptides. To better understand the pathological consequences of inapprop...

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Detalles Bibliográficos
Autores principales: Kim, Chul, Srivastava, Sapeckshita, Rice, Marian, Godenschwege, Tanja A, Bentley, Brooke, Ravi, Saranya, Shao, Shuang, Woodard, Craig T, Schwartz, Lawrence M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112101/
https://www.ncbi.nlm.nih.gov/pubmed/21518451
http://dx.doi.org/10.1186/1472-6793-11-7

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