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GRISOTTO: A greedy approach to improve combinatorial algorithms for motif discovery with prior knowledge
BACKGROUND: Position-specific priors (PSP) have been used with success to boost EM and Gibbs sampler-based motif discovery algorithms. PSP information has been computed from different sources, including orthologous conservation, DNA duplex stability, and nucleosome positioning. The use of prior info...
Autores principales: | Carvalho, Alexandra M, Oliveira, Arlindo L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112114/ https://www.ncbi.nlm.nih.gov/pubmed/21513505 http://dx.doi.org/10.1186/1748-7188-6-13 |
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