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Dengue Virus Tropism in Humanized Mice Recapitulates Human Dengue Fever
Animal models of dengue virus disease have been very difficult to develop because of the virus' specificity for infection and replication in certain human cells. We developed a model of dengue fever in immunodeficient mice transplanted with human stem cells from umbilical cord blood. These mice...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112147/ https://www.ncbi.nlm.nih.gov/pubmed/21695193 http://dx.doi.org/10.1371/journal.pone.0020762 |