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G protein-coupled receptor kinase 5 mediates Tazarotene-induced gene 1-induced growth suppression of human colon cancer cells

BACKGROUND: Tazarotene-induced gene 1 (TIG1) is a retinoid-inducible type II tumour suppressor gene. The B isoform of TIG1 (TIG1B) inhibits growth and invasion of cancer cells. Expression of TIG1B is frequently downregulated in various cancer tissues; however, the expression and activities of the TI...

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Detalles Bibliográficos
Autores principales:	Wu, Chang-Chieh, Tsai, Fu-Ming, Shyu, Rong-Yaun, Tsai, Ya-Ming, Wang, Chun-Hua, Jiang, Shun-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112162/ https://www.ncbi.nlm.nih.gov/pubmed/21575264 http://dx.doi.org/10.1186/1471-2407-11-175

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