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Targeting of Voltage-Gated Calcium Channel α(2)δ-1 Subunit to Lipid Rafts Is Independent from a GPI-Anchoring Motif

Voltage-gated calcium channels (Ca(v)) exist as heteromultimers comprising a pore-forming α(1) with accessory β and α(2)δ subunits which modify channel trafficking and function. We previously showed that α(2)δ-1 (and likely the other mammalian α(2)δ isoforms - α(2)δ-2, 3 and 4) is required for targe...

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Detalles Bibliográficos
Autores principales: Robinson, Philip, Etheridge, Sarah, Song, Lele, Shah, Riddhi, Fitzgerald, Elizabeth M., Jones, Owen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112168/
https://www.ncbi.nlm.nih.gov/pubmed/21695204
http://dx.doi.org/10.1371/journal.pone.0019802

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