8-Chloro-Cyclic AMP and Protein Kinase A I-Selective Cyclic AMP Analogs Inhibit Cancer Cell Growth through Different Mechanisms

Cyclic AMP (cAMP) inhibits the proliferation of several tumor cells. We previously reported an antiproliferative effect of PKA I-selective cAMP analogs (8-PIP-cAMP and 8-HA-cAMP) on two human cancer cell lines of different origin. 8-Cl-cAMP, another cAMP analog with known antiproliferative propertie...

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Detalles Bibliográficos
Autores principales: Lucchi, Simona, Calebiro, Davide, de Filippis, Tiziana, Grassi, Elisa S., Borghi, Maria Orietta, Persani, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112188/
https://www.ncbi.nlm.nih.gov/pubmed/21695205
http://dx.doi.org/10.1371/journal.pone.0020785

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