Selecting synaptic partners: GRASPing the role of UNC-6/netrin

Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local UNC-6/netrin signaling in...

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Detalles Bibliográficos
Autor principal: Ch'ng, QueeLim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112191/
https://www.ncbi.nlm.nih.gov/pubmed/21663686
http://dx.doi.org/10.1186/1741-7007-9-43
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author Ch'ng, QueeLim
author_facet Ch'ng, QueeLim
author_sort Ch'ng, QueeLim
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description Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets. See Research article: http://www.neuraldevelopment.com/content/6/1/28
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spelling pubmed-31121912011-06-11 Selecting synaptic partners: GRASPing the role of UNC-6/netrin Ch'ng, QueeLim BMC Biol Commentary Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets. See Research article: http://www.neuraldevelopment.com/content/6/1/28 BioMed Central 2011-06-10 /pmc/articles/PMC3112191/ /pubmed/21663686 http://dx.doi.org/10.1186/1741-7007-9-43 Text en Copyright ©2011 Ch'ng; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Ch'ng, QueeLim
Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_full Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_fullStr Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_full_unstemmed Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_short Selecting synaptic partners: GRASPing the role of UNC-6/netrin
title_sort selecting synaptic partners: grasping the role of unc-6/netrin
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112191/
https://www.ncbi.nlm.nih.gov/pubmed/21663686
http://dx.doi.org/10.1186/1741-7007-9-43
work_keys_str_mv AT chngqueelim selectingsynapticpartnersgraspingtheroleofunc6netrin

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