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Protective Effects of Positive Lysosomal Modulation in Alzheimer's Disease Transgenic Mouse Models

Alzheimer's disease (AD) is an age-related neurodegenerative pathology in which defects in proteolytic clearance of amyloid β peptide (Aβ) likely contribute to the progressive nature of the disorder. Lysosomal proteases of the cathepsin family exhibit up-regulation in response to accumulating p...

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Detalles Bibliográficos
Autores principales:	Butler, David, Hwang, Jeannie, Estick, Candice, Nishiyama, Akiko, Kumar, Saranya Santhosh, Baveghems, Clive, Young-Oxendine, Hollie B., Wisniewski, Meagan L., Charalambides, Ana, Bahr, Ben A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112200/ https://www.ncbi.nlm.nih.gov/pubmed/21695208 http://dx.doi.org/10.1371/journal.pone.0020501

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