Asc-Dependent and Independent Mechanisms Contribute to Restriction of Legionella Pneumophila Infection in Murine Macrophages

The apoptosis-associated speck-like protein containing a caspase recruitment domain (Asc) is an adaptor molecule that mediates inflammatory and apoptotic signals. Legionella pneumophila is an intracellular bacterium and the causative agent of Legionnaire's pneumonia. L. pneumophila is able to c...

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Detalles Bibliográficos
Autores principales: Abdelaziz, Dalia H. A., Gavrilin, Mikhail A., Akhter, Anwari, Caution, Kyle, Kotrange, Sheetal, Khweek, Arwa Abu, Abdulrahman, Basant A., Hassan, Zeinab A., El-Sharkawi, Fathia Z., Bedi, Simranjit S., Ladner, Katherine, Gonzalez-Mejia, M. Elba, Doseff, Andrea I., Mostafa, Mahmoud, Kanneganti, Thirumala-Devi, Guttridge, Dennis, Marsh, Clay B., Wewers, Mark D., Amer, Amal O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112328/
https://www.ncbi.nlm.nih.gov/pubmed/21713115
http://dx.doi.org/10.3389/fmicb.2011.00018

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