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Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis

BACKGROUND: Inferring viral tropism from genotype is a fast and inexpensive alternative to phenotypic testing. While being highly predictive when performed on clonal samples, sensitivity of predicting CXCR4-using (X4) variants drops substantially in clinical isolates. This is mainly attributed to mi...

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Detalles Bibliográficos
Autores principales:	Däumer, Martin, Kaiser, Rolf, Klein, Rolf, Lengauer, Thomas, Thiele, Bernhard, Thielen, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112379/ https://www.ncbi.nlm.nih.gov/pubmed/21569501 http://dx.doi.org/10.1186/1472-6947-11-30

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