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A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells

BACKGROUND: WS070117 is a novel small molecule compound that significantly improves lipid metabolism disorders in high-fat-diet (HFD) induced hyperlipidemia in hamsters. METHODS AND RESULTS: We evaluated liver/body weight ratio, liver histology, serum and hepatic lipid content in HFD-fed hamsters tr...

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Detalles Bibliográficos
Autores principales: Lian, Zeqin, Li, Yan, Gao, Jian, Qu, Kai, Li, Jin, Hao, Linghua, Wu, Song, Zhu, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112420/
https://www.ncbi.nlm.nih.gov/pubmed/21529359
http://dx.doi.org/10.1186/1476-511X-10-67