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α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes

AIMS: Lipid accumulation in non-adipose tissues leads to cell dysfunction and apoptosis, a phenomenon known as lipotoxicity. Unsaturated fatty acids may offset the lipotoxicity associated with saturated fatty acids. Stearic acid induced endoplasmic reticulum (ER) stress and caused apoptotic and necr...

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Detalles Bibliográficos
Autores principales:	Zhang, Yong, Dong, Lei, Yang, Xia, Shi, Hongyang, Zhang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112425/ https://www.ncbi.nlm.nih.gov/pubmed/21592363 http://dx.doi.org/10.1186/1476-511X-10-81

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