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Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus

Synchronous oscillations of thousands of cellular clocks in the suprachiasmatic nucleus (SCN), the circadian centre, are coordinated by precisely timed cell–cell communication, the principle of which is largely unknown. Here we show that the amount of RGS16 (regulator of G protein signalling 16), a...

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Detalles Bibliográficos
Autores principales: Doi, Masao, Ishida, Atsushi, Miyake, Akiko, Sato, Miho, Komatsu, Rie, Yamazaki, Fumiyoshi, Kimura, Ikuo, Tsuchiya, Soken, Kori, Hiroshi, Seo, Kazuyuki, Yamaguchi, Yoshiaki, Matsuo, Masahiro, Fustin, Jean-Michel, Tanaka, Rina, Santo, Yasuko, Yamada, Hiroyuki, Takahashi, Yukari, Araki, Michihiro, Nakao, Kazuki, Aizawa, Shinichi, Kobayashi, Masaki, Obrietan, Karl, Tsujimoto, Gozoh, Okamura, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112533/
https://www.ncbi.nlm.nih.gov/pubmed/21610730
http://dx.doi.org/10.1038/ncomms1316

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