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Transcription factor IRF8 directs a silencing programme for T(H)17 cell differentiation

T(H)17 cells are recognized as a unique subset of T helper cells that have critical roles in the pathogenesis of autoimmunity and tissue inflammation. Although RORγt is necessary for the generation of T(H)17 cells, the molecular mechanisms underlying the functional diversity of T(H)17 cells are not...

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Detalles Bibliográficos
Autores principales:	Ouyang, Xinshou, Zhang, Ruihua, Yang, Jianjun, Li, Qingshan, Qin, Lihui, Zhu, Chen, Liu, Jianguo, Ning, Huan, Shin, Min Sun, Gupta, Monica, Qi, Chen-Feng, He, John Cijiang, Lira, Sergio A., Morse, Herbert C., Ozato, Keiko, Mayer, Lloyd, Xiong, Huabao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112536/ https://www.ncbi.nlm.nih.gov/pubmed/21587231 http://dx.doi.org/10.1038/ncomms1311

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