Laparoscopic Splenectomy in a Patient with Acquired Angioneurotic Edema

BACKGROUND: We report the case of a 77-year-old female with acquired angioneurotic edema, C1 esterase inhibitor level = 4mg/dL, who was scheduled to undergo a laparoscopic splenectomy. METHODS: In the operating room, we administered on call 500 units (UI) of C1 esterase inhibitor concentrate intrave...

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Autores principales: Jabbour-Khoury, Samar, Khoury, Ghattas, Soueide, Antoine, Baraka, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Laparoendoscopic Surgeons 2000
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113192/
https://www.ncbi.nlm.nih.gov/pubmed/11051190
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author Jabbour-Khoury, Samar
Khoury, Ghattas
Soueide, Antoine
Baraka, Anis
author_facet Jabbour-Khoury, Samar
Khoury, Ghattas
Soueide, Antoine
Baraka, Anis
author_sort Jabbour-Khoury, Samar
collection PubMed
description BACKGROUND: We report the case of a 77-year-old female with acquired angioneurotic edema, C1 esterase inhibitor level = 4mg/dL, who was scheduled to undergo a laparoscopic splenectomy. METHODS: In the operating room, we administered on call 500 units (UI) of C1 esterase inhibitor concentrate intravenously. Intraoperative hemodynamic instability and generalized blood oozing improved following the administration of aprotinin 250000 UI intravenous (IV) drip. CONCLUSION: We recommend the administration of an antifibrinolytic agent in addition to C1 esterase inhibitor concentrate in patients with acquired angioneurotic edema.
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spelling pubmed-31131922011-07-12 Laparoscopic Splenectomy in a Patient with Acquired Angioneurotic Edema Jabbour-Khoury, Samar Khoury, Ghattas Soueide, Antoine Baraka, Anis JSLS Case Reports BACKGROUND: We report the case of a 77-year-old female with acquired angioneurotic edema, C1 esterase inhibitor level = 4mg/dL, who was scheduled to undergo a laparoscopic splenectomy. METHODS: In the operating room, we administered on call 500 units (UI) of C1 esterase inhibitor concentrate intravenously. Intraoperative hemodynamic instability and generalized blood oozing improved following the administration of aprotinin 250000 UI intravenous (IV) drip. CONCLUSION: We recommend the administration of an antifibrinolytic agent in addition to C1 esterase inhibitor concentrate in patients with acquired angioneurotic edema. Society of Laparoendoscopic Surgeons 2000 /pmc/articles/PMC3113192/ /pubmed/11051190 Text en © 2000 by JSLS, Journal of the Society of Laparoendoscopic Surgeons. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits for noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited and is not altered in any way.
spellingShingle Case Reports
Jabbour-Khoury, Samar
Khoury, Ghattas
Soueide, Antoine
Baraka, Anis
Laparoscopic Splenectomy in a Patient with Acquired Angioneurotic Edema
title Laparoscopic Splenectomy in a Patient with Acquired Angioneurotic Edema
title_full Laparoscopic Splenectomy in a Patient with Acquired Angioneurotic Edema
title_fullStr Laparoscopic Splenectomy in a Patient with Acquired Angioneurotic Edema
title_full_unstemmed Laparoscopic Splenectomy in a Patient with Acquired Angioneurotic Edema
title_short Laparoscopic Splenectomy in a Patient with Acquired Angioneurotic Edema
title_sort laparoscopic splenectomy in a patient with acquired angioneurotic edema
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113192/
https://www.ncbi.nlm.nih.gov/pubmed/11051190
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AT soueideantoine laparoscopicsplenectomyinapatientwithacquiredangioneuroticedema
AT barakaanis laparoscopicsplenectomyinapatientwithacquiredangioneuroticedema

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