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Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions

BACKGROUND: Synthetic lethal genetic interactions among proteins have been widely used to define functional relationships between proteins and pathways. However, the molecular mechanism of synthetic lethal genetic interactions is still unclear. RESULTS: In this study, we demonstrated that yeast synt...

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Detalles Bibliográficos
Autores principales: Li, Bo, Cao, Weiguo, Zhou, Jizhong, Luo, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113237/
https://www.ncbi.nlm.nih.gov/pubmed/21586150
http://dx.doi.org/10.1186/1752-0509-5-73