AKAP150-mediated TRPV1 sensitization is disrupted by calcium/calmodulin

BACKGROUND: The transient receptor potential vanilloid type1 (TRPV1) is expressed in nociceptive sensory neurons and is sensitive to phosphorylation. A-Kinase Anchoring Protein 79/150 (AKAP150) mediates phosphorylation of TRPV1 by Protein Kinases A and C, modulating channel activity. However, few st...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaudhury, Sraboni, Bal, Manjot, Belugin, Sergei, Shapiro, Mark S, Jeske, Nathaniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113319/
https://www.ncbi.nlm.nih.gov/pubmed/21569553
http://dx.doi.org/10.1186/1744-8069-7-34

Ejemplares similares

Ejemplares similares