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Genome-wide chromatin occupancy analysis reveals a role for ASH2 in transcriptional pausing

An important mechanism for gene regulation involves chromatin changes via histone modification. One such modification is histone H3 lysine 4 trimethylation (H3K4me3), which requires histone methyltranferase complexes (HMT) containing the trithorax-group (trxG) protein ASH2. Mutations in ash2 cause a...

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Detalles Bibliográficos
Autores principales: Pérez-Lluch, Sílvia, Blanco, Enrique, Carbonell, Albert, Raha, Debasish, Snyder, Michael, Serras, Florenci, Corominas, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113561/
https://www.ncbi.nlm.nih.gov/pubmed/21310711
http://dx.doi.org/10.1093/nar/gkq1322