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Translational recoding as a feedback controller: systems approaches reveal polyamine-specific effects on the antizyme ribosomal frameshift

The antizyme protein, Oaz1, regulates synthesis of the polyamines putrescine, spermidine and spermine by controlling stability of the polyamine biosynthetic enzyme, ornithine decarboxylase. Antizyme mRNA translation depends upon a polyamine-stimulated +1 ribosomal frameshift, forming a complex negat...

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Detalles Bibliográficos
Autores principales:	Rato, Claudia, Amirova, Svetlana R., Bates, Declan G., Stansfield, Ian, Wallace, Heather M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113565/ https://www.ncbi.nlm.nih.gov/pubmed/21303766 http://dx.doi.org/10.1093/nar/gkq1349

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