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Strand bias influences the mechanism of gene editing directed by single-stranded DNA oligonucleotides

Gene editing directed by modified single-stranded DNA oligonucleotides has been used to alter a single base pair in a variety of biological systems. It is likely that gene editing is facilitated by the direct incorporation of the oligonucleotides via replication and/or by direct conversion, most lik...

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Detalles Bibliográficos
Autores principales: Falgowski, Kerry, Falgowski, Carly, York-Vickers, Cassie, Kmiec, Eric B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113578/
https://www.ncbi.nlm.nih.gov/pubmed/21343181
http://dx.doi.org/10.1093/nar/gkr061