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GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells
BACKGROUND: Growth-differentiation factor-15 (GDF-15) is a stress-responsive, transforming growth factor-β-related cytokine, which has recently been reported to be elevated in serum of patients with idiopathic pulmonary arterial hypertension (IPAH). The aim of the study was to examine the expression...
Autores principales: | Nickel, Nils, Jonigk, Danny, Kempf, Tibor, Bockmeyer, Clemens L, Maegel, Lavinia, Rische, Johanna, Laenger, Florian, Lehmann, Ulrich, Sauer, Clemens, Greer, Mark, Welte, Tobias, Hoeper, Marius M, Golpon, Heiko A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113721/ https://www.ncbi.nlm.nih.gov/pubmed/21548946 http://dx.doi.org/10.1186/1465-9921-12-62 |
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