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Gene expression profiles in BCL11B-siRNA treated malignant T cells

BACKGROUND: Downregulation of the B-cell chronic lymphocytic leukemia (CLL)/lymphoma11B (BCL11B) gene by small interfering RNA (siRNA) leads to growth inhibition and apoptosis of the human T-cell acute lymphoblastic leukemia (T-ALL) cell line Molt-4. To further characterize the molecular mechanism,...

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Detalles Bibliográficos
Autores principales: Huang, Xin, Shen, Qi, Chen, Si, Chen, Shaohua, Yang, Lijian, Weng, Jianyu, Du, Xin, Grabarczyk, Piotr, Przybylski, Grzegorz K, Schmidt, Christian A, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113752/
https://www.ncbi.nlm.nih.gov/pubmed/21575156
http://dx.doi.org/10.1186/1756-8722-4-23