Histone deacetylase activity is necessary for left-right patterning during vertebrate development

BACKGROUND: Consistent asymmetry of the left-right (LR) axis is a crucial aspect of vertebrate embryogenesis. Asymmetric gene expression of the TGFβ superfamily member Nodal related 1 (Nr1) in the left lateral mesoderm plate is a highly conserved step regulating the situs of the heart and viscera. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Carneiro, Katia, Donnet, Claudia, Rejtar, Tomas, Karger, Barry L, Barisone, Gustavo A, Díaz, Elva, Kortagere, Sandhya, Lemire, Joan M, Levin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113753/
https://www.ncbi.nlm.nih.gov/pubmed/21599922
http://dx.doi.org/10.1186/1471-213X-11-29

Ejemplares similares

Ejemplares similares