Cargando…

GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration

RhoU is an atypical Rho family member with high homology to CDC42 but containing unique N- and C-terminal extensions. The mechanisms regulating RhoU activation, as well as its downstream effectors, are not fully characterized. We show that after epidermal growth factor (EGF) stimulation RhoU colocal...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jin-San, Koenig, Alexander, Young, Charles, Billadeau, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113775/
https://www.ncbi.nlm.nih.gov/pubmed/21508312
http://dx.doi.org/10.1091/mbc.E10-12-0969