Non-Apical Membrane Antigen 1 (AMA1) IgGs from Malian Children Interfere with Functional Activity of AMA1 IgGs as Judged by Growth Inhibition Assay

BACKGROUND: Apical membrane antigen 1 (AMA1) is one of the best-studied blood-stage malaria vaccine candidates. When an AMA1 vaccine was tested in a malaria naïve population, it induced functionally active antibodies judged by Growth Inhibition Assay (GIA). However, the same vaccine failed to induce...

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Detalles Bibliográficos
Autores principales: Miura, Kazutoyo, Perera, Suwani, Brockley, Sarah, Zhou, Hong, Aebig, Joan A., Moretz, Samuel E., Miller, Louis H., Doumbo, Ogobara K., Sagara, Issaka, Dicko, Alassane, Ellis, Ruth D., Long, Carole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113848/
https://www.ncbi.nlm.nih.gov/pubmed/21695140
http://dx.doi.org/10.1371/journal.pone.0020947

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