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Expression Profiling of FSHD-1 and FSHD-2 Cells during Myogenic Differentiation Evidences Common and Distinctive Gene Dysregulation Patterns

BACKGROUND: Determine global gene dysregulation affecting 4q-linked (FSHD-1) and non 4q-linked (FSHD-2) cells during early stages of myogenic differentiation. This approach has been never applied to FSHD pathogenesis. METHODOLOGY/PRINCIPAL FINDINGS: By in vitro differentiation of FSHD-1 and FSHD-2 m...

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Detalles Bibliográficos
Autores principales: Cheli, Stefania, François, Stephanie, Bodega, Beatrice, Ferrari, Francesco, Tenedini, Elena, Roncaglia, Enrica, Ferrari, Sergio, Ginelli, Enrico, Meneveri, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113851/
https://www.ncbi.nlm.nih.gov/pubmed/21695143
http://dx.doi.org/10.1371/journal.pone.0020966