Gene Constellation of Influenza A Virus Reassortants with High Growth Phenotype Prepared as Seed Candidates for Vaccine Production

BACKGROUND: Influenza A virus vaccines undergo yearly reformulations due to the antigenic variability of the virus caused by antigenic drift and shift. It is critical to the vaccine manufacturing process to obtain influenza A seed virus that is antigenically identical to circulating wild type (wt) v...

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Detalles Bibliográficos
Autores principales: Fulvini, Andrew A., Ramanunninair, Manojkumar, Le, Jianhua, Pokorny, Barbara A., Arroyo, Jennifer Minieri, Silverman, Jeanmarie, Devis, Rene, Bucher, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113853/
https://www.ncbi.nlm.nih.gov/pubmed/21695145
http://dx.doi.org/10.1371/journal.pone.0020823

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