Cargando…
BMP9 Protects Septal Neurons from Axotomy-Evoked Loss of Cholinergic Phenotype
BACKGROUND: Cholinergic projection from the septum to the hippocampus is crucial for normal cognitive function and degeneration of cells and nerve fibers within the septohippocampal pathway contributes to the pathophysiology of Alzheimer's disease. Bone morphogenetic protein (BMP) 9 is a cholin...
Autores principales: | Lopez-Coviella, Ignacio, Mellott, Tiffany J., Schnitzler, Aletta C., Blusztajn, Jan K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113905/ https://www.ncbi.nlm.nih.gov/pubmed/21695154 http://dx.doi.org/10.1371/journal.pone.0021166 |
Ejemplares similares
-
Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons
por: Lazo, Oscar M, et al.
Publicado: (2010) -
IGF2 Ameliorates Amyloidosis, Increases Cholinergic Marker Expression and Raises BMP9 and Neurotrophin Levels in the Hippocampus of the APPswePS1dE9 Alzheimer’s Disease Model Mice
por: Mellott, Tiffany J., et al.
Publicado: (2014) -
Intrinsic Cholinergic Neurons in the Hippocampus: Fact or Artifact?
por: Blusztajn, Jan Krzysztof, et al.
Publicado: (2016) -
Calcium in Neuronal and Glial Response to Axotomy
por: Khaitin, Andrey
Publicado: (2021) -
Intrinsic response of thoracic propriospinal neurons to axotomy
por: Siebert, Justin R, et al.
Publicado: (2010)