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Human Immunodeficiency Virus Type 1 Vif causes dysfunction of Cdk1 and CyclinB1: implications for cell cycle arrest

The two major cytopathic factors in human immunodeficiency virus type 1 (HIV-1), the accessory proteins viral infectivity factor (Vif) and viral protein R (Vpr), inhibit cell-cycle progression at the G2 phase of the cell cycle. Although Vpr-induced blockade and the associated T-cell death have been...

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Detalles Bibliográficos
Autores principales:	Sakai, Keiko, Barnitz, R Anthony, Chaigne-Delalande, Benjamin, Bidère, Nicolas, Lenardo, Michael J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113979/ https://www.ncbi.nlm.nih.gov/pubmed/21569376 http://dx.doi.org/10.1186/1743-422X-8-219

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