Cargando…
EAPP: Gatekeeper at the crossroad of apoptosis and p21-mediated cell-cycle arrest
We previously identified and characterized E2F-associated phospho-protein (EAPP), a nuclear phosphoprotein that interacts with the activating members of the E2F transcription factor family. EAPP levels are frequently elevated in transformed human cells. To examine the biological relevance of EAPP, w...
Autores principales: | Andorfer, P, Rotheneder, H |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114185/ https://www.ncbi.nlm.nih.gov/pubmed/21258403 http://dx.doi.org/10.1038/onc.2010.639 |
Ejemplares similares
-
Telomere uncapping at the crossroad between cell cycle arrest and carcinogenesis
por: Gobbini, Elisa, et al.
Publicado: (2014) -
Syk-Targeted, a New 3-Arylbenzofuran Derivative EAPP-2 Blocks Airway Inflammation of Asthma–COPD Overlap in vivo and in vitro
por: Li, Shuyi, et al.
Publicado: (2021) -
Palbociclib-mediated cell cycle arrest can occur in the absence of the CDK inhibitors p21 and p27
por: Pennycook, Betheney R., et al.
Publicado: (2021) -
Loss of IKKβ activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosis
por: Yang, Pei-Ming, et al.
Publicado: (2010) -
Body temperature cycles: Gatekeepers of circadian clocks
por: Morf, Jörg, et al.
Publicado: (2013)