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Real-time full field laser Doppler imaging
We present a full field laser Doppler imaging instrument, which enables real-time in vivo assessment of blood flow in dermal tissue and skin. This instrument monitors the blood perfusion in an area of about 50 cm(2) with 480 × 480 pixels per frame at a rate of 12–14 frames per second. Smaller frames...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Optical Society of America
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114216/ https://www.ncbi.nlm.nih.gov/pubmed/21698011 http://dx.doi.org/10.1364/BOE.2.001470 |
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author | Leutenegger, Marcel Martin-Williams, Erica Harbi, Pascal Thacher, Tyler Raffoul, Wassim André, Marc Lopez, Antonio Lasser, Philippe Lasser, Theo |
author_facet | Leutenegger, Marcel Martin-Williams, Erica Harbi, Pascal Thacher, Tyler Raffoul, Wassim André, Marc Lopez, Antonio Lasser, Philippe Lasser, Theo |
author_sort | Leutenegger, Marcel |
collection | PubMed |
description | We present a full field laser Doppler imaging instrument, which enables real-time in vivo assessment of blood flow in dermal tissue and skin. This instrument monitors the blood perfusion in an area of about 50 cm(2) with 480 × 480 pixels per frame at a rate of 12–14 frames per second. Smaller frames can be monitored at much higher frame rates. We recorded the microcirculation in healthy skin before, during and after arterial occlusion. In initial clinical case studies, we imaged the microcirculation in burned skin and monitored the recovery of blood flow in a skin flap during reconstructive surgery indicating the high potential of LDI for clinical applications. Small animal imaging in mouse ears clearly revealed the network of blood vessels and the corresponding blood perfusion. |
format | Online Article Text |
id | pubmed-3114216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Optical Society of America |
record_format | MEDLINE/PubMed |
spelling | pubmed-31142162011-06-22 Real-time full field laser Doppler imaging Leutenegger, Marcel Martin-Williams, Erica Harbi, Pascal Thacher, Tyler Raffoul, Wassim André, Marc Lopez, Antonio Lasser, Philippe Lasser, Theo Biomed Opt Express Functional Imaging We present a full field laser Doppler imaging instrument, which enables real-time in vivo assessment of blood flow in dermal tissue and skin. This instrument monitors the blood perfusion in an area of about 50 cm(2) with 480 × 480 pixels per frame at a rate of 12–14 frames per second. Smaller frames can be monitored at much higher frame rates. We recorded the microcirculation in healthy skin before, during and after arterial occlusion. In initial clinical case studies, we imaged the microcirculation in burned skin and monitored the recovery of blood flow in a skin flap during reconstructive surgery indicating the high potential of LDI for clinical applications. Small animal imaging in mouse ears clearly revealed the network of blood vessels and the corresponding blood perfusion. Optical Society of America 2011-05-09 /pmc/articles/PMC3114216/ /pubmed/21698011 http://dx.doi.org/10.1364/BOE.2.001470 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially. |
spellingShingle | Functional Imaging Leutenegger, Marcel Martin-Williams, Erica Harbi, Pascal Thacher, Tyler Raffoul, Wassim André, Marc Lopez, Antonio Lasser, Philippe Lasser, Theo Real-time full field laser Doppler imaging |
title | Real-time full field laser Doppler imaging |
title_full | Real-time full field laser Doppler imaging |
title_fullStr | Real-time full field laser Doppler imaging |
title_full_unstemmed | Real-time full field laser Doppler imaging |
title_short | Real-time full field laser Doppler imaging |
title_sort | real-time full field laser doppler imaging |
topic | Functional Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114216/ https://www.ncbi.nlm.nih.gov/pubmed/21698011 http://dx.doi.org/10.1364/BOE.2.001470 |
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