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Ultrasmall spot size scanning laser ophthalmoscopy

An ultrasmall spot size scanning laser ophthalmoscope has been developed that employs an annular aberration-corrected incident beam to increase the effective numerical aperture of the eye thereby reducing the width of the probing light spot. Parafovea and foveal cone photoreceptor visibility determi...

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Detalles Bibliográficos
Autores principales: Vohnsen, Brian, Rativa, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114227/
https://www.ncbi.nlm.nih.gov/pubmed/21698022
http://dx.doi.org/10.1364/BOE.2.001597
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author Vohnsen, Brian
Rativa, Diego
author_facet Vohnsen, Brian
Rativa, Diego
author_sort Vohnsen, Brian
collection PubMed
description An ultrasmall spot size scanning laser ophthalmoscope has been developed that employs an annular aberration-corrected incident beam to increase the effective numerical aperture of the eye thereby reducing the width of the probing light spot. Parafovea and foveal cone photoreceptor visibility determined from small area retinal image scans are discussed from the perspective of mode matching between the focused incident beam and the waveguide modes of individual cones. The cone visibility near the fovea centralis can be increased with the annular illumination scheme whereas the visibility of larger parafovea cones drops significantly as a consequence of poorer mode match. With further improvements of the implemented wavefront correction technology it holds promise for individual cone-photoreceptor imaging at the fovea centralis and for optical targeting of the retina with increased resolution.
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spelling pubmed-31142272011-06-22 Ultrasmall spot size scanning laser ophthalmoscopy Vohnsen, Brian Rativa, Diego Biomed Opt Express Ophthalmology Applications An ultrasmall spot size scanning laser ophthalmoscope has been developed that employs an annular aberration-corrected incident beam to increase the effective numerical aperture of the eye thereby reducing the width of the probing light spot. Parafovea and foveal cone photoreceptor visibility determined from small area retinal image scans are discussed from the perspective of mode matching between the focused incident beam and the waveguide modes of individual cones. The cone visibility near the fovea centralis can be increased with the annular illumination scheme whereas the visibility of larger parafovea cones drops significantly as a consequence of poorer mode match. With further improvements of the implemented wavefront correction technology it holds promise for individual cone-photoreceptor imaging at the fovea centralis and for optical targeting of the retina with increased resolution. Optical Society of America 2011-05-18 /pmc/articles/PMC3114227/ /pubmed/21698022 http://dx.doi.org/10.1364/BOE.2.001597 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Ophthalmology Applications
Vohnsen, Brian
Rativa, Diego
Ultrasmall spot size scanning laser ophthalmoscopy
title Ultrasmall spot size scanning laser ophthalmoscopy
title_full Ultrasmall spot size scanning laser ophthalmoscopy
title_fullStr Ultrasmall spot size scanning laser ophthalmoscopy
title_full_unstemmed Ultrasmall spot size scanning laser ophthalmoscopy
title_short Ultrasmall spot size scanning laser ophthalmoscopy
title_sort ultrasmall spot size scanning laser ophthalmoscopy
topic Ophthalmology Applications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114227/
https://www.ncbi.nlm.nih.gov/pubmed/21698022
http://dx.doi.org/10.1364/BOE.2.001597
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