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Reflective afocal broadband adaptive optics scanning ophthalmoscope

A broadband adaptive optics scanning ophthalmoscope (BAOSO) consisting of four afocal telescopes, formed by pairs of off-axis spherical mirrors in a non-planar arrangement, is presented. The non-planar folding of the telescopes is used to simultaneously reduce pupil and image plane astigmatism. The...

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Detalles Bibliográficos
Autores principales: Dubra, Alfredo, Sulai, Yusufu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114240/
https://www.ncbi.nlm.nih.gov/pubmed/21698035
http://dx.doi.org/10.1364/BOE.2.001757
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author Dubra, Alfredo
Sulai, Yusufu
author_facet Dubra, Alfredo
Sulai, Yusufu
author_sort Dubra, Alfredo
collection PubMed
description A broadband adaptive optics scanning ophthalmoscope (BAOSO) consisting of four afocal telescopes, formed by pairs of off-axis spherical mirrors in a non-planar arrangement, is presented. The non-planar folding of the telescopes is used to simultaneously reduce pupil and image plane astigmatism. The former improves the adaptive optics performance by reducing the root-mean-square (RMS) of the wavefront and the beam wandering due to optical scanning. The latter provides diffraction limited performance over a 3 diopter (D) vergence range. This vergence range allows for the use of any broadband light source(s) in the 450-850 nm wavelength range to simultaneously image any combination of retinal layers. Imaging modalities that could benefit from such a large vergence range are optical coherence tomography (OCT), multi- and hyper-spectral imaging, single- and multi-photon fluorescence. The benefits of the non-planar telescopes in the BAOSO are illustrated by resolving the human foveal photoreceptor mosaic in reflectance using two different superluminescent diodes with 680 and 796 nm peak wavelengths, reaching the eye with a vergence of 0.76 D relative to each other.
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spelling pubmed-31142402011-06-22 Reflective afocal broadband adaptive optics scanning ophthalmoscope Dubra, Alfredo Sulai, Yusufu Biomed Opt Express Ophthalmology Applications A broadband adaptive optics scanning ophthalmoscope (BAOSO) consisting of four afocal telescopes, formed by pairs of off-axis spherical mirrors in a non-planar arrangement, is presented. The non-planar folding of the telescopes is used to simultaneously reduce pupil and image plane astigmatism. The former improves the adaptive optics performance by reducing the root-mean-square (RMS) of the wavefront and the beam wandering due to optical scanning. The latter provides diffraction limited performance over a 3 diopter (D) vergence range. This vergence range allows for the use of any broadband light source(s) in the 450-850 nm wavelength range to simultaneously image any combination of retinal layers. Imaging modalities that could benefit from such a large vergence range are optical coherence tomography (OCT), multi- and hyper-spectral imaging, single- and multi-photon fluorescence. The benefits of the non-planar telescopes in the BAOSO are illustrated by resolving the human foveal photoreceptor mosaic in reflectance using two different superluminescent diodes with 680 and 796 nm peak wavelengths, reaching the eye with a vergence of 0.76 D relative to each other. Optical Society of America 2011-05-27 /pmc/articles/PMC3114240/ /pubmed/21698035 http://dx.doi.org/10.1364/BOE.2.001757 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Ophthalmology Applications
Dubra, Alfredo
Sulai, Yusufu
Reflective afocal broadband adaptive optics scanning ophthalmoscope
title Reflective afocal broadband adaptive optics scanning ophthalmoscope
title_full Reflective afocal broadband adaptive optics scanning ophthalmoscope
title_fullStr Reflective afocal broadband adaptive optics scanning ophthalmoscope
title_full_unstemmed Reflective afocal broadband adaptive optics scanning ophthalmoscope
title_short Reflective afocal broadband adaptive optics scanning ophthalmoscope
title_sort reflective afocal broadband adaptive optics scanning ophthalmoscope
topic Ophthalmology Applications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114240/
https://www.ncbi.nlm.nih.gov/pubmed/21698035
http://dx.doi.org/10.1364/BOE.2.001757
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