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Diazoxide-Unresponsive Congenital Hyperinsulinism in Children With Dominant Mutations of the β-Cell Sulfonylurea Receptor SUR1

OBJECTIVE: Congenital hyperinsulinemic hypoglycemia is a group of genetic disorders of insulin secretion most commonly associated with inactivating mutations of the β-cell ATP-sensitive K(+) channel (K(ATP) channel) genes ABCC8 (SUR1) and KCNJ11 (Kir6.2). Recessive mutations of these genes cause hyp...

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Detalles Bibliográficos
Autores principales:	MacMullen, Courtney M., Zhou, Qing, Snider, Kara E., Tewson, Paul H., Becker, Susan A., Aziz, Ali Rahim, Ganguly, Arupa, Shyng, Show-Ling, Stanley, Charles A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114386/ https://www.ncbi.nlm.nih.gov/pubmed/21536946 http://dx.doi.org/10.2337/db10-1631

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