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The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway

APPL1 is an adaptor protein that binds to both AKT and adiponectin receptors and is hypothesised to mediate the effects of adiponectin in activating downstream effectors such as AMP-activated protein kinase (AMPK). We aimed to establish whether APPL1 plays a physiological role in mediating glycogen...

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Detalles Bibliográficos
Autores principales:	Cleasby, M E, Lau, Q, Polkinghorne, E, Patel, S A, Leslie, S J, Turner, N, Cooney, G J, Xu, A, Kraegen, E W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioScientifica 2011
Materias:	Regular Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114475/ https://www.ncbi.nlm.nih.gov/pubmed/21543456 http://dx.doi.org/10.1530/JOE-11-0039

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