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Variants of GCKR Affect Both β-Cell and Kidney Function in Patients With Newly Diagnosed Type 2 Diabetes: The Verona Newly Diagnosed Type 2 Diabetes Study 2

OBJECTIVE: In genome-wide association studies, performed mostly in nondiabetic individuals, genetic variability of glucokinase regulatory protein (GCKR) affects type 2 diabetes-related phenotypes, kidney function, and risk of chronic kidney disease (CKD). We tested whether GCKR variability affects t...

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Detalles Bibliográficos
Autores principales: Bonetti, Sara, Trombetta, Maddalena, Boselli, Maria Linda, Turrini, Fabiola, Malerba, Giovanni, Trabetti, Elisabetta, Pignatti, Pier Franco, Bonora, Enzo, Bonadonna, Riccardo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114499/
https://www.ncbi.nlm.nih.gov/pubmed/21411509
http://dx.doi.org/10.2337/dc10-2218