Genetic and epigenetic factors: Role in male infertility

Genetic factors contribute upto 15%–30% cases of male infertility. Formation of spermatozoa occurs in a sequential manner with mitotic, meiotic, and postmeiotic differentiation phases each of which is controlled by an intricate genetic program. Genes control a variety of physiologic processes, such...

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Detalles Bibliográficos
Autores principales: Shamsi, M. B., Kumar, K., Dada, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Symposium
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114572/
https://www.ncbi.nlm.nih.gov/pubmed/21716934
http://dx.doi.org/10.4103/0970-1591.78436
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author Shamsi, M. B.
Kumar, K.
Dada, R.
author_facet Shamsi, M. B.
Kumar, K.
Dada, R.
author_sort Shamsi, M. B.
collection PubMed
description Genetic factors contribute upto 15%–30% cases of male infertility. Formation of spermatozoa occurs in a sequential manner with mitotic, meiotic, and postmeiotic differentiation phases each of which is controlled by an intricate genetic program. Genes control a variety of physiologic processes, such as hypothalamus–pituitary–gonadal axis, germ cell development, and differentiation. In the era of assisted reproduction technology, it is important to understand the genetic basis of infertility to provide maximum adapted therapeutics and counseling to the couple.
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spelling pubmed-31145722011-06-28 Genetic and epigenetic factors: Role in male infertility Shamsi, M. B. Kumar, K. Dada, R. Indian J Urol Symposium Genetic factors contribute upto 15%–30% cases of male infertility. Formation of spermatozoa occurs in a sequential manner with mitotic, meiotic, and postmeiotic differentiation phases each of which is controlled by an intricate genetic program. Genes control a variety of physiologic processes, such as hypothalamus–pituitary–gonadal axis, germ cell development, and differentiation. In the era of assisted reproduction technology, it is important to understand the genetic basis of infertility to provide maximum adapted therapeutics and counseling to the couple. Medknow Publications 2011 /pmc/articles/PMC3114572/ /pubmed/21716934 http://dx.doi.org/10.4103/0970-1591.78436 Text en Copyright: © Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Symposium
Shamsi, M. B.
Kumar, K.
Dada, R.
Genetic and epigenetic factors: Role in male infertility
title Genetic and epigenetic factors: Role in male infertility
title_full Genetic and epigenetic factors: Role in male infertility
title_fullStr Genetic and epigenetic factors: Role in male infertility
title_full_unstemmed Genetic and epigenetic factors: Role in male infertility
title_short Genetic and epigenetic factors: Role in male infertility
title_sort genetic and epigenetic factors: role in male infertility
topic Symposium
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114572/
https://www.ncbi.nlm.nih.gov/pubmed/21716934
http://dx.doi.org/10.4103/0970-1591.78436
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