A rare case of plasmacytoid urothelial carcinoma of bladder: Diagnostic dilemmas and clinical implications

Plasmacytoid urothelial carcinoma is an uncommon and aggressive variant of urothelial carcinoma associated with late presentation and poor prognosis. We discuss here the first reported case from India of a 54-year-old male who presented with hematuria. Cystoscopy showed edematous and ulcerated mucos...

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Autores principales: Rahman, Khaliqur, Menon, Santosh, Patil, Asawari, Bakshi, Ganesh, Desai, Sangeeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Uropathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114580/
https://www.ncbi.nlm.nih.gov/pubmed/21716882
http://dx.doi.org/10.4103/0970-1591.78409
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author Rahman, Khaliqur
Menon, Santosh
Patil, Asawari
Bakshi, Ganesh
Desai, Sangeeta
author_facet Rahman, Khaliqur
Menon, Santosh
Patil, Asawari
Bakshi, Ganesh
Desai, Sangeeta
author_sort Rahman, Khaliqur
collection PubMed
description Plasmacytoid urothelial carcinoma is an uncommon and aggressive variant of urothelial carcinoma associated with late presentation and poor prognosis. We discuss here the first reported case from India of a 54-year-old male who presented with hematuria. Cystoscopy showed edematous and ulcerated mucosa throughout the bladder. A transurethral biopsy revealed urothelial carcinoma with plasmacytoid appearance. He underwent a radial cystectomy which on histopathology showed plasmacytoid urothelial carcinoma of the bladder of high stage with involvement up to bladder serosa and adventitial walls of the ureter. The diagnostic dilemmas of this unusual variant of urothelial malignancy and its clinical impact are discussed.
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spelling pubmed-31145802011-06-28 A rare case of plasmacytoid urothelial carcinoma of bladder: Diagnostic dilemmas and clinical implications Rahman, Khaliqur Menon, Santosh Patil, Asawari Bakshi, Ganesh Desai, Sangeeta Indian J Urol Uropathology Plasmacytoid urothelial carcinoma is an uncommon and aggressive variant of urothelial carcinoma associated with late presentation and poor prognosis. We discuss here the first reported case from India of a 54-year-old male who presented with hematuria. Cystoscopy showed edematous and ulcerated mucosa throughout the bladder. A transurethral biopsy revealed urothelial carcinoma with plasmacytoid appearance. He underwent a radial cystectomy which on histopathology showed plasmacytoid urothelial carcinoma of the bladder of high stage with involvement up to bladder serosa and adventitial walls of the ureter. The diagnostic dilemmas of this unusual variant of urothelial malignancy and its clinical impact are discussed. Medknow Publications 2011 /pmc/articles/PMC3114580/ /pubmed/21716882 http://dx.doi.org/10.4103/0970-1591.78409 Text en Copyright: © Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Uropathology
Rahman, Khaliqur
Menon, Santosh
Patil, Asawari
Bakshi, Ganesh
Desai, Sangeeta
A rare case of plasmacytoid urothelial carcinoma of bladder: Diagnostic dilemmas and clinical implications
title A rare case of plasmacytoid urothelial carcinoma of bladder: Diagnostic dilemmas and clinical implications
title_full A rare case of plasmacytoid urothelial carcinoma of bladder: Diagnostic dilemmas and clinical implications
title_fullStr A rare case of plasmacytoid urothelial carcinoma of bladder: Diagnostic dilemmas and clinical implications
title_full_unstemmed A rare case of plasmacytoid urothelial carcinoma of bladder: Diagnostic dilemmas and clinical implications
title_short A rare case of plasmacytoid urothelial carcinoma of bladder: Diagnostic dilemmas and clinical implications
title_sort rare case of plasmacytoid urothelial carcinoma of bladder: diagnostic dilemmas and clinical implications
topic Uropathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114580/
https://www.ncbi.nlm.nih.gov/pubmed/21716882
http://dx.doi.org/10.4103/0970-1591.78409
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