Cargando…

Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element

BACKGROUND: The human genome harbors several largely preserved HERV-K(HML-2) elements. Although this retroviral family comes closest of all known HERVs to producing replication competent virions, mutations acquired during their chromosomal residence have rendered them incapable of expressing infecti...

Descripción completa

Detalles Bibliográficos
Autores principales:	George, Maja, Schwecke, Torsten, Beimforde, Nadine, Hohn, Oliver, Chudak, Claudia, Zimmermann, Anja, Kurth, Reinhard, Naumann, Dieter, Bannert, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114732/ https://www.ncbi.nlm.nih.gov/pubmed/21554716 http://dx.doi.org/10.1186/1742-4690-8-30

Ejemplares similares

CMV-Promoter Driven Codon-Optimized Expression Alters the Assembly Type and Morphology of a Reconstituted HERV-K(HML-2)
por: Hohn, Oliver, et al.
Publicado: (2014)

HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease
por: Hohn, Oliver, et al.
Publicado: (2013)

Identification of late assembly domains of the human endogenous retrovirus-K(HML-2)
por: Chudak, Claudia, et al.
Publicado: (2013)

Identification of late assembly domains of the human endogenous retrovirus-K(HML-2)
por: Chudak, Claudia, et al.
Publicado: (2013)

Ancient Adversary – HERV-K (HML-2) in Cancer
por: Dervan, Eoin, et al.
Publicado: (2021)

Reconstitution, age estimation and expression of the Human Endogenous Retrovirus K113 with its original sequence present at the time of integration
por: Bannert, Norbert, et al.
Publicado: (2009)

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins
por: Mayer, Jens, et al.
Publicado: (2018)

Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci
por: Grandi, Nicole, et al.
Publicado: (2020)

Comprehensive identification and characterization of the HERV-K (HML-9) group in the human genome
por: Jia, Lei, et al.
Publicado: (2022)

Identification of differentially expressed HERV-K(HML-2) loci in colorectal cancer
por: Kang, Qian, et al.
Publicado: (2023)

Exploring HERV-K (HML-2) Influence in Cancer and Prospects for Therapeutic Interventions
por: Costa, Bárbara, et al.
Publicado: (2023)

Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers
por: de Mulder, Miguel, et al.
Publicado: (2017)

Not all viruses cause disease: HERV-K(HML-2) in healthy human tissues
por: Srinivasachar Badarinarayan, Smitha, et al.
Publicado: (2022)

Transcriptional Profiling of Human Endogenous Retrovirus Group HERV-K(HML-2) Loci in Melanoma
por: Schmitt, Katja, et al.
Publicado: (2013)

The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation
por: Broecker, Felix, et al.
Publicado: (2016)

High Expression of HERV-K (HML-2) Might Stimulate Interferon in COVID-19 Patients
por: Guo, Yaolin, et al.
Publicado: (2022)

Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues
por: Burn, Aidan, et al.
Publicado: (2022)

Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
por: Scognamiglio, Sante, et al.
Publicado: (2022)

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project
por: Flockerzi, Aline, et al.
Publicado: (2008)

Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses
por: Subramanian, Ravi P, et al.
Publicado: (2011)

Significant Upregulation of HERV-K (HML-2) Transcription Levels in Human Lung Cancer and Cancer Cells
por: Yang, Caiqin, et al.
Publicado: (2022)

HERVs New Role in Cancer: From Accused Perpetrators to Cheerful Protectors
por: Bannert, Norbert, et al.
Publicado: (2018)

Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion
por: Grandi, Nicole, et al.
Publicado: (2017)

Preferential expression of human endogenous retrovirus K (HERV-K/HML-2) type 1 in tumor cells
por: Romano, Camila M, et al.
Publicado: (2011)

Differential Expression of HERV-K (HML-2) Proviruses in Cells and Virions of the Teratocarcinoma Cell Line Tera-1
por: Bhardwaj, Neeru, et al.
Publicado: (2015)

Effect of aging on the transcriptomic changes associated with the expression of the HERV-K (HML-2) provirus at 1q22
por: Autio, Arttu, et al.
Publicado: (2020)

Differential expression of an endogenous retroviral element [HERV-K(HML-6)] is associated with reduced survival in glioblastoma patients
por: Shah, Ashish H., et al.
Publicado: (2022)

HERV-K(HML7) Integrations in the Human Genome: Comprehensive Characterization and Comparative Analysis in Non-Human Primates
por: Grandi, Nicole, et al.
Publicado: (2021)

Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity
por: Monde, Kazuaki, et al.
Publicado: (2017)

HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues
por: Schmitt, Katja, et al.
Publicado: (2015)

Increased HERV-K(HML-2) Transcript Levels Correlate with Clinical Parameters of Liver Damage in Hepatitis C Patients
por: Weber, Melanie, et al.
Publicado: (2021)

Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants
por: Chabukswar, Saili, et al.
Publicado: (2022)

Vaccination directed against the human endogenous retrovirus-K (HERV-K) gag protein slows HERV-K gag expressing cell growth in a murine model system
por: Kraus, Benjamin, et al.
Publicado: (2014)

Generation, Characterization and Application of Antibodies Directed against HERV-H Gag Protein in Colorectal Samples
por: Mullins, Christina S., et al.
Publicado: (2016)

Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
por: Tatkiewicz, Witold, et al.
Publicado: (2020)

Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2
por: Zhao, Yao, et al.
Publicado: (2022)

Correction to: Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines
por: Tatkiewicz, Witold, et al.
Publicado: (2020)

Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein
por: Nangola, Sawitree, et al.
Publicado: (2012)

Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec
por: Ruggieri, Alessia, et al.
Publicado: (2009)

Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection
por: Michaud, Henri-Alexandre, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_tjaonblclnc5g30vv7kkofrpvs