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Meta-Alignment with Crumble and Prune: Partitioning very large alignment problems for performance and parallelization

BACKGROUND: Continuing research into the global multiple sequence alignment problem has resulted in more sophisticated and principled alignment methods. Unfortunately these new algorithms often require large amounts of time and memory to run, making it nearly impossible to run these algorithms on la...

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Detalles Bibliográficos
Autores principales: Roskin, Krishna M, Paten, Benedict, Haussler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114744/
https://www.ncbi.nlm.nih.gov/pubmed/21569267
http://dx.doi.org/10.1186/1471-2105-12-144