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Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies

BACKGROUND: Genomic aberrations can be used to determine cancer diagnosis and prognosis. Clinically relevant novel aberrations can be discovered using high-throughput assays such as Single Nucleotide Polymorphism (SNP) arrays and next-generation sequencing, which typically provide aggregate signals...

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Detalles Bibliográficos
Autores principales:	Parisi, Fabio, Ariyan, Stephan, Narayan, Deepak, Bacchiocchi, Antonella, Hoyt, Kathleen, Cheng, Elaine, Xu, Fang, Li, Peining, Halaban, Ruth, Kluger, Yuval
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114747/ https://www.ncbi.nlm.nih.gov/pubmed/21569352 http://dx.doi.org/10.1186/1471-2164-12-230

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