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A Multicentre Randomized Controlled Trial of the Efficacy and Safety of Single-Dose Praziquantel at 40 mg/kg vs. 60 mg/kg for Treating Intestinal Schistosomiasis in the Philippines, Mauritania, Tanzania and Brazil

BACKGROUND: Praziquantel at 40 mg/kg in a single dose is the WHO recommended treatment for all forms of schistosomiasis, but 60 mg/kg is also deployed nationally. METHODOLOGY/PRINCIPAL FINDINGS: Four trial sites in the Philippines, Mauritania, Tanzania and Brazil enrolled 856 patients using a common...

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Detalles Bibliográficos
Autores principales: Olliaro, Piero L., Vaillant, Michel T., Belizario, Vincente J., Lwambo, Nicholas J. S., Ouldabdallahi, Mohamed, Pieri, Otavio S., Amarillo, Maria L., Kaatano, Godfrey M., Diaw, Mamadou, Domingues, AnaLucia C., Favre, Tereza C., Lapujade, Olivier, Alves, Fabiana, Chitsulo, Lester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114749/
https://www.ncbi.nlm.nih.gov/pubmed/21695161
http://dx.doi.org/10.1371/journal.pntd.0001165