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Humanized Rag1(−/−)γc(−/−) Mice Support Multilineage Hematopoiesis and Are Susceptible to HIV-1 Infection via Systemic and Vaginal Routes

Several new immunodeficient mouse models for human cell engraftment have recently been introduced that include the Rag2(−/−)γc(−/−), NOD/SCID, NOD/SCIDγc(−/−) and NOD/SCIDβ2m(−/−) strains. Transplantation of these mice with CD34(+) human hematopoietic stem cells leads to prolonged engraftment, multi...

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Detalles Bibliográficos
Autores principales:	Akkina, Ramesh, Berges, Bradford K., Palmer, Brent E., Remling, Leila, Neff, C. Preston, Kuruvilla, Jes, Connick, Elizabeth, Folkvord, Joy, Gagliardi, Kathy, Kassu, Afework, Akkina, Sarah R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114781/ https://www.ncbi.nlm.nih.gov/pubmed/21695116 http://dx.doi.org/10.1371/journal.pone.0020169

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