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Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes

BACKGROUND: Osteonecrosis of the femoral head is a common complication of high-dose glucocorticoid treatment. Intravascular thrombosis is thought to be associated with the ischemic state of the femoral head. Plasminogen activator inhibitor-1 (PAI-1) is an adipokine, which are physiologically active...

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Detalles Bibliográficos
Autores principales:	Sakamoto, Kazutaka, Osaki, Makoto, Hozumi, Akira, Goto, Hisataka, Fukushima, Tatsuya, Baba, Hideo, Shindo, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114799/ https://www.ncbi.nlm.nih.gov/pubmed/21524281 http://dx.doi.org/10.1186/1471-2474-12-82

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