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Dynamics of Cdk1 Substrate Specificity during the Cell Cycle

Cdk specificity is determined by the intrinsic selectivity of the active site and by substrate docking sites on the cyclin subunit. There is a long-standing debate about the relative importance of these factors in the timing of Cdk1 substrate phosphorylation. We analyzed major budding yeast cyclins...

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Detalles Bibliográficos
Autores principales: Kõivomägi, Mardo, Valk, Ervin, Venta, Rainis, Iofik, Anna, Lepiku, Martin, Morgan, David O., Loog, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115021/
https://www.ncbi.nlm.nih.gov/pubmed/21658602
http://dx.doi.org/10.1016/j.molcel.2011.05.016

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