Cargando…
Dynamics of Cdk1 Substrate Specificity during the Cell Cycle
Cdk specificity is determined by the intrinsic selectivity of the active site and by substrate docking sites on the cyclin subunit. There is a long-standing debate about the relative importance of these factors in the timing of Cdk1 substrate phosphorylation. We analyzed major budding yeast cyclins...
Autores principales: | Kõivomägi, Mardo, Valk, Ervin, Venta, Rainis, Iofik, Anna, Lepiku, Martin, Morgan, David O., Loog, Mart |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115021/ https://www.ncbi.nlm.nih.gov/pubmed/21658602 http://dx.doi.org/10.1016/j.molcel.2011.05.016 |
Ejemplares similares
-
Double-negative feedback between S-phase cyclin-CDK and CKI generates abruptness in the G1/S switch
por: Venta, Rainis, et al.
Publicado: (2012) -
Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase
por: Kõivomägi, Mardo, et al.
Publicado: (2011) -
Multisite phosphorylation networks as signal processors for Cdk1
por: Kõivomägi, Mardo, et al.
Publicado: (2013) -
Cyclin-Specific Docking Mechanisms Reveal the Complexity of M-CDK Function in the Cell Cycle
por: Örd, Mihkel, et al.
Publicado: (2019) -
Multistep phosphorylation systems: tunable components of biological signaling circuits
por: Valk, Evin, et al.
Publicado: (2014)